Oncotrex 5 Tablet 10'S

Methotrexate 5Mg
10 Tablets in 1 strip

Delivery date: 1 - 3 days

Rs 132.00

Strip

Methotrexate belongs to a class of drugs known as antimetabolites which is used to treat severe psoriasis and and certain forms of rheumatoid arthritis. It works by interfering and slowing or stopping the growth of certain cells in the body, especially those cells that reproduce quickly

It is used to treat:

Active rheumatoid arthritis in adult patients
Severe psoriatic arthritis in adult patients
Certain types of cancer of the breast, skin, head and neck, or lung

Are allergic to methotrexate or any other ingredient of this medicine
Have significant liver disease
Have significant kidney disease
Have or have had a bone marrow disease or serious blood disorders
Are allergic to Methotrexate or any of the other ingredients of this medicine
Have an impaired immune system
Have severe acute or existing infections e.g Tuberculosis or HIV
Have inflammation or ulcers in your mouth
Have active phase gastrointestinal ulcers (e.g. peptic ulcer or ulcerative colitis)
Suffer from diabetes mellitus and being treated with insulin
Have received any vaccinations recently
Have inactive, prolonged infections (e.g. Tuberculosis, Hepatitis B or C, Shingles [herpes zoster])
Have had ulcerations in your stomach or bowel
Are in poor general condition
Have problems with lung function
Are severely overweight
Have abnormal accumulation of liquid in the abdomen or in the cavity between the lungs and chest wall (ascites, pleural effusions)
Are dehydrated or suffer from conditions leading to dehydration (e.g. Dehydration as a result of vomiting, Diarrhoea or Inflammation of the mouth and lips)

This medicine is not recommended if you are pregnant or planning to have a baby as it can cause birth defects, harm the unborn child or cause miscarriages. Ask your doctor for advise before taking this medicine
This medicine is not recommended if you are breast feeding or planning to breast feed as it passes into breast milk. Ask your doctor for advise before taking this medicine

Alcohol is not recommended while taking this medicine

This medicine may make you feel fatigue and dizziness. If this happens, do not drive or operate any machinery

Please inform your doctor in case you are taking any of the following medicines:

Penicillins, Glycopeptides, Ciprofloxacin, Cefalotin, Sulfonamides, Trimethoprim/Sulfamethoxazole, Tetracycline and Chloramphenicol
Sulfasalazine and Leflunomide
Doxorubicin, Cisplatin, Mercaptopurine
Phenytoin, or Levetiracetam
Cholestyramine
Diclofenac and Ibuprofen, Aspirin, Metamizole
Omeprazole or Pantoprazole
Diuretics, Triamterene
Metformin
Probenecid
Theophylline
Cyclosporine
Barbiturates
Tranquillisers
Oral contraceptives
Azathioprine, Leflunomide, Sulphasalazine, Phenylbutazone, or Amidopyrine
Retinoids
Pyrimethamine
Vitamin preparations containing folic acid
Any vaccination with a live vaccine (must be avoided), such as Measles, mumps, Influenza or Yellow fever vaccines

Always take these tablets exactly as your doctor has told you
The tablets should be swallowed whole with a drink of water while sitting upright or standing

If you forget to use this medicine:

Take it as soon as possible
Do not double the dose

If you stop using this medicine:

Do not stop taking this medicine without your doctor’s advice

Stomatitis, Dyspepsia, Anorexia, Nausea,Vomiting, Abdominal pain
Abnormal liver function tests

Infections
Leucopenia
Headache, Drowsiness, Dizziness, Fatigue
Oral ulcers, Diarrhoea
Erythematous rash, Alopaecia, Exanthema

Opportunistic infections
Lymphoma
Bone marrow depression, Agranulocytosis, Thrombocytopenia, Anaemia, Hematopoietic disorders
Anaphylactic-type reaction
Vertigo
Pneumonia, Interstitial pneumonitis, Interstitial/ pulmonary fibrosis
Decrease in serum albumin, Fatty degeneration of the liver
Pruritus, Stevens-Johnson´s syndrome, Toxic epidermal necrolysis, Herpetiform eruptions of the skin, Increased skin pigmentation
Osteoporosis, Arthralgia, Myalgia, Increased rheumatic nodules
Renal insufficiency, Nephropathy, Inflammation and ulceration of the urinary bladder, Disturbed micturition, Dysuria
Vaginal inflammation and ulceration
Chills

Herpes zoster, Sepsis
Megaloblastic anemia
Diabetes mellitus
Depression, Confusion, Mood alterations
Hemiparesis, Paresis
Pericarditis, Pericardial effusion, Pericardial tamponade
Hypotension, Thromboembolism
Dyspnoea, Pharyngitis, Respiratory paralysis
Gingivitis, Gastrointestinal ulcerations and haemorrhage, Enteritis, Melaena
Hepatotoxicity, Periportal fibrosis,Liver cirrhosis, Acute hepatitis
Photohypersensitivity, Acne, Depigmentation, Urticaria, Erythema multiforme, Painful damage to psoriatic lesion, Skin ulceration, Onycholysis, Increased nail pigment changes, Petechiae, Allergic vasculitis, Radiation dermatitis and sunburn may be “recalled”
Stress fracture
Oliguria, Anuria, Electrolyte disturbances, Azotaemia
Decreased libido, Impotence, Menstrual disorders
Fever, Wound-healing impairmen, Asthenia

Hypogammag-lobulinaemia, Lympho-proliferative disorders, Lymphadeno-pathy, Neutropenia, Aplastic anemia
Immuno-suppression
Insomnia, Psychoses
Irritation, Dysarthria, Aphasia, Lethargy, Cerebral oedema, Transient subtle cognitive dysfunction, Unusual cranial sensation, Convulsions, Pain, muscular asthenia or paraesthesia in the extremities, Changes in sense of taste (metallic taste), Meningism, Acute aseptic meningitis, Paralysis
Conjunctivitis, Blurred vision
Tinnitus
Vasculitis
Pneumocystis jiroveci – pneumonia and other lung infections, Chronic interstitial obstructive lung disease, Pleuritis, Pleural effusion, Dry cough
Haematemesis
Reactivation of chronic hepatitis, Hepatic failure
Telangiectasis, Furunculosis, Ecchymoses, Hidradenitis, Acute paronchynia
Haematuria
Formation of defective oocytes or sperm cells, Transient oligospermia, Infertility, Vaginal bleeding, Vaginal discharge, Gynaecomastia

Keep out of the reach and sight of children
This medicine must not be used after the expiry date
Store at room temperature (15-25°C)

webmd.com | drugs.com | medicine.org.uk | netmeds.com

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